6-BroMo-4-chloroquinazoline.HCl salt (38267-96-8)

(2 Customer hōʻike manaʻo)

Ke noho nei kēia huahana ma kahi palapala pāʻani APICMO.

Ka hiki ke hana, synthesi a hana i nā mea nui o ka 6-BroMo-4-chloroquinazoline.HCl paʻakai (38267-96-8) me ka pūnaewele mana maikaʻi ma lalo o ka ulahana CGMP
nā kauā.

Māhele:

Description

6-BroMo-4-chloroquinazoline.HCl paʻakai (38267-96-8) wikiō

6-BroMo-4-chloroquinazoline.HCl salt (38267-96-8)Specifications

CAS 38267-96-8
Ke kaʻina CAS% 95.0
Kālena CAS Max% 100.0
MDL Number ʻO MFCD01862191
InChI Key InChIKey = JFJNDMNYNYLFLJ-UHFFFAOYSA-N
Ka inoa inoa inoa 6-BroMo-4-chloroquinazoline.HCl paʻakai
Pāʻani infrared pono
ʻO ke Kino Ka lepo lūlū
'ōpala ʻO ka'ōmole Glass
Ka Lā Molecular C8H4BrClN2
Molecular Weight (g / mol) 243.49
SMILES ClC1 = C2C = C (Br) C = CC2 = NC = N1
kala like 'ole Beige
Point Hoʻolālā 160-165 ° C
ʻAna 95%

6-BroMo-4-chloroquinazoline.HCl paʻakai (38267-96-8) Mālama a mālama

(38267-96-8) Hōʻikeʻikepili:

◆ Hanaʻia kaʻili o kaʻili

◆ Hana i nā maka o ka maka

◆ Hana paha i ka huhū o ka hanu

ʻO nā'āpana'ōpala APICMO

6-BroMo-4-chloroquinazoline.HCl paʻakai Nānā hoʻomaopopo:

◆ E hōʻalo i ka hoʻomahaʻana i ka lepo / fume / gas / mist / vapors / spray.

◆ E holoi i kaʻili ma hope pono o ka lawelaweʻana.

◆ E hoʻohana wale i waho a ma kahi hoʻomaha maikaʻi.

◆ Nā pale pale pale / pale pale / pale maka / maka

mālama.

◆ Inā ma kaʻili: E holoi me ka huʻona a me ka wai.

◆ Inā hoʻonāukiʻia: E hoʻokuʻu i ka mea pepehi i ka ea hou a hoʻomaha i ka

kahi kūlana no ka hanuʻana.

◆ Inā i nā maka: E hoʻomau pono me ka wai no nā minuke.

◆ E hoʻokaʻawale i nā leka hulina, ināʻoi aku a maʻalahi paha. E hoʻomau

ka holoiʻana.

◆ Kelepona i kahi pokapū lāʻauʻino a kauka paha ināʻikeʻoe heʻole.

◆ Ke kaulike kaulike (e nānā i nā kulekele kōkua mua ma kēia

lepili).

◆ Ināʻoi aku ka huhū o ke kino: E loaʻa i ka leka aʻo / nānā.

◆ Inā mau ka huhū i ka maka: E loaʻa i ka leka aʻo / kaumana.

◆ E wehe i nā lole maʻemaʻe a holoi i mua o ka hoʻohana hou.

◆ E kūʻai i kahi wahi maikaʻi. E hoʻopaʻa paʻa i ka pahu.

◆ E kūʻai i ka loka.

◆ E hoʻouna i nā mea / pahu i kahi hoʻokuʻuʻiaʻana o ka waohue

meakanu.

'Ōlelo Aʻo: Ua hoʻokumuʻia kaʻike i hoʻolakoʻia ma kēia pūnaewele e like me nā kānāwai o ka Europa (EU) a ua kūpono i ka maikaʻi o ko mākouʻike, kaʻike a me ka manaʻo i ka lā o kona hoʻolahaʻana. ʻO kaʻike i hāʻawiʻia i kūkuluʻia wale nōʻo ia ke alakaʻi no ka mālama pono a hoʻohanaʻana. ʻAʻole pono e noʻonoʻoʻia e like me ke kikowaena a iʻole ke kiko kiko'ī.

6-BroMo-4-chloroquinazoline.HCl paʻakai (38267-96-8) Nā'Ōlelo

Ke Kuhi o Pahuhiho E a me Tryptanthrin ma o ka Hoʻopauʻana / Cyclization Cascade

Hoʻomākaukauʻia ka mea hoʻohana i ka biomimetically mai ka methyl indole-3-carboxylate a me ka methyl anthranilala a iʻole ka anthranilic acid e hoʻohana ana i ka hui ester e like me ka hui hana.

Helvetica Chimica Acta 2018 vol. 101 # 2,

Ka Kuʻuna Hua'ōlelo maikaʻi loa o ka Quinazoline a me Benzopyrano [2,3-d] pyrimidine mau mea hoʻohālike i hoʻopiliʻia e N-Bromosulfonamides

N, N, N ', N'-tetrabromobenzene-1,3-disulfonamide a me ka Poly (N, N'-dibromo-N-'eto-benzene-1,3-disulfonamide) i hoʻohana like efficient catalysts no kekahi-ipu hoʻololi kemikala o hou quinazoline nā mea loaʻa, mai ilahi aldehydes ...

Ka Nūpepa o ka Hua'ōlelo Kiʻi Hua'ōleloʻo 2017. 54 # 1 p. 215 - 225,

Nānā Hanahana:

Loaʻa kaʻike o kā mākou pūʻuluʻepekema ma nā wahi noiʻi a pau e pili ana i Life Science, Material Science, Synthesis Chemical, Chromatography, Analytical a me nā mea'ē aʻe.

6-BroMo-4-chloroquinazoline.HCl paʻakai (38267-96-8) Kūlana Hoʻolaha & Pricing:

Loaʻa i nā mea nui no kāu kūkuluʻana, hana hana a noiʻi noiʻi paha?


=

2 hōʻike manaʻo no ka mea, 6-BroMo-4-chloroquinazoline.HCl salt (38267-96-8)

  1. APICMO -

    Hoʻokomo mākou i ka momona nui loa o ka nui o ke keleponaʻenehana nui a me ka nui. ʻO kā mākou hana i ke laina me ka pūnaehana hoʻonohonohoʻenehana a me nā kūlana cGMP.

    ʻO ke kumu hoʻohālikelike o ka 6-Bromo-4-chloroquinazoline.HCl paʻakai (38267-96-8);

    6-BroMo-4-chloroquinazoline.HCl paʻakai (38267-96-8) -APICMO

    No ka 6-Bromo-4-chloroquinazoline.HCl paʻakai (38267-96-8)

    6-Bromo-4-chloroquinazoline.HCL paʻakai ka paʻakai o ka quinazolines, he mau heterocyclic pū e hōʻike ana i nā mea lapaʻau.

    ʻO ka hōʻailona o ka hanaʻeleʻele o KY04031, ka mea hoʻokūkū PAK4 (PAK4 IC50 = 0.790MM), ke kumu mua o kaʻikeʻana i ka mechanical o ka holomuaʻana o ka maʻi. ʻO ka hoʻohālikelikeʻana i nā mea hoʻokipa PAK4 e kau nui ma luna o ka hale aniani. Ma o kēia loiloi, ua hoʻokumu mākou i ka likelika e hoʻololi i ka triazinecore KY04031 i kahi quinazoline.With KY04031 e like me ka pūnaewele kuhikuhi, ua hoʻomaka mākou ma ka hanaʻana a me ka synthesizing i nā hua'ōlelo kūikawā o 2,4-diaminoquinazoline.

    Ma ka māheleʻana o nā huahana hoʻopiʻi PAK4 i nā huahana synthesi, uaʻike mākou i ka heluPAK4 IC50 = 0.033μM.ʻO kēia pūpū, iʻikeʻoleʻia he 9d, hoʻonāukiuki nuiʻia ka G1 phase cell cell.It kahe i ka hoʻoukaʻana o nā pūnaewele A549, nā mea i kuleana no ka hōʻikeʻana iā PAK4. No laila, aia ka mana o PAK4-LIMK1 path signaling. No ka loaʻa o kā mākou mauʻike, ua hōʻaha mākou i ka pūnaewele 9 i loaʻa i ka lāʻau lapaʻau kūikawā a me kahi noiʻi noiʻi no ke ola kinoʻana o PAK4.

    I ka manawa o ka quinazoline a me ka newbenzopyrano [2,3-d] pyrimidine huapalapa mai nā aldehydes, ammonium acetate, a me 2-amino-benzophene, poly (N, N'-dibromo-N-ethylbenzene-1,3-disulfonamide) a me N, N , N ', N'-tetrabromobenzene-1,3-1,3-disulfonamidehaa i nā mea nui catalysts.These mea hana catalytic e hua mai ana i nā hua kiʻekiʻe .Quhuaʻia nā kapalima e ka nui o nā aldehydes, ammonium acetate, a me 2-amino-benzophene aʻo benzopyrano [2,3-d] pyrimidine loaʻa i nā amineʻonika maʻamau, salicyclic aldehydes, a me ka malonitrile.

    Nā hoʻohana o 6-Bromo-4-chloroquinazoline.HCL paʻakai

    Hoʻohanaʻia ka huahana e like me ke kauka lāʻau lapaʻau no kaʻikeʻana i ka lāʻauʻawaʻawa anti-cancer.

    38267-96-8 Hōʻike Huahana

    Ka pae paila (˚C) 339.7
    ʻAʻole CAS no. 38267-96-8
    Inoa inoa inoa 6-Bromo-4-chloroquinazoline.HCL paʻakai
    'Aiha (g / cm3) 1.763
    Keʻano hoʻolālā C8H4BrClN2
    Pākuhi Flash (˚C) 159.24
    Kālā kūmole (g / mol) 243.488
    Inoa IUPAC 6-Bromo-4-chloroquinazoline
    Wahi hoʻolālā (° C) 160 - 165
    Ka monoisotopic mass (g / mol) 241.925
    Ke Kuleana paa
    Purity 95%
    ʻO ke kumuhana hana 6-BroMo-4-chloroquinazoline.HCl salt (38267-96-8)
    'O Synonyms · 4-chloro-6-bromoquinazoline
    · 6-bromo-4-chloro-quinazoline hydrochloride
    · Quinazoline, 6-bromo-4-chloro-

    NĀ Kino & NĀ Kino Kino o 6-Bromo-4-chloroquinazoline (38267-96-8)

    Hōʻikeʻia ka 38267-96-8

    6-Bromo-4-chloroquinazoline (38267-96-8) he paʻakikī koʻikoʻi, e paʻa ana i ka paukū.

    Hoʻohui

    Kohu 1
    Kahi paʻa wai Helu helu Donor -ʻaʻohe
    Helu helu kiʻi - 2
    ʻO ke kūʻokoʻa hiki ke kaʻa 0

    Nā 38267-96-8 Mea Hana i hoʻoiliʻia

    Kahi inoa ʻO ke kumu waiwai
    XLogP3-AA 3.2
    Ka helu helu hōʻemiʻole 0
    ʻO ka heluʻo Atom Stereocenter 0
    Wahi puni pola 25.78A '2
    Ke kele 'āpana (dyne / cm) 60.83
    Hōʻike kuhikuhi 1.691
    Hoʻomākaukauʻo Isotope Atom 0
    Heluhelu Atomona Heavy 12
    Kāleka Kūikawā 0
    ʻIke kūpono (g / mol) 241.925
    ʻO ka komoʻana o ka vaporization (kJ / mol) 56.008
    Ka Heluhelu Hoʻohālike Bond Bond 0
    Hoʻomākaukau'Āina Atom 0
    Hoʻokomoʻia ka papahana oiaio
    Ka nui 167

    6-Bromo-4-chloroquinazoline (38267-96-8) Hōʻike Hōhā.

    6-BroMo-4-chloroquinazoline.HCl salt (38267-96-8)

    6-Bromo-4-chloroquinazoline Nā huahana mua

    6-BroMo-4-chloroquinazoline.HCl salt (38267-96-8)

    Nā huahana Downstream

    6-BroMo-4-chloroquinazoline.HCl salt (38267-96-8)

    6-Bromo-4-chloroquinazoline (38267-96-8) GHS Hazard Description

    ʻO nā'āpana'ōpala APICMO

    6-Bromo-4-chloroquinazoline ua hoʻohālikeʻia heʻano hauʻoli. He mea ia e hoʻonāʻia ai nā maka, ka hanu makani, a iʻole kaʻili, e pili ana i ke kiko o ka hulina. Hiki ke huhū a hoʻomau i ka huhū, ma mua o nā maka, e hiki ai ke kūpono i ka hala. ʻO kekahi o nā hōʻailona paʻakikī e pili ana i kaʻiliʻana o kaʻili, ka wai uila, kaʻeha, ka liʻiliʻi, ka umauma, kaʻili, a me ka uila. Inā kōkuaʻia ke kōkua mua i ka manawa maikaʻi, hiki ke hoʻopilikiaʻia kaʻino ma lalo.

    6-Bromo-4-chloroquinazoline Kaʻina Hana Puʻe

    Handling6-Bromo-4-chloroquinazoline (38267-96-8)

    Ke Kuleana pilikino

    Hoʻohui wale i ka 6-Bromo-4-chloroquinazoline.HCl paʻakai (38267-96-8) i ka wā i loaʻa ai iāʻoe kaʻike piha a me kaʻike pū me nā mea waiwai weliweli a me nā palekana e pili ana. Ināʻaʻoheʻikeʻoleʻoe, e hoʻohana iā ia ma lalo o ka nānāʻana o ka mea hoʻohana kūpono.

    Eʻaʻahu i nā mea hana palekana i'āponoʻia e like me nā kānāwai o ka palekana hoʻolālā maʻamau. E uhi i ka helehelena me ka pale maka maʻamau piha, nā aniani aniani, a hoʻohana i ka hanu hauʻoli, e like me nā kānāwai NIOSH a me EN. Ke lawe i nā kāmaʻa kaumaha kaumaha a me nā mīkina limaʻole.

    Eia kekahi, e hōʻoiaʻoe e hana i loko o ka hale hana hoʻolālā i hoʻolālā maikaʻiʻia i ka hale hoʻoulu a me ka maloʻoʻana no ka hoʻomaʻemaʻeʻana i ka ea a me ka holoʻana. Ināʻaʻole kāu wahi hana paʻa, e hoʻohana i ka huahana i waho.ʻAʻoleʻoe e hanu i ka lepo, vapors, fumes, aiʻole ke kinoea.

    Ka mālama o 6-Bromo-4-chloroquinazoline

    E kūʻai i ka huahana ma kahi maloʻo a me ka makani aʻike pono e hiki ke hoʻoponopono i nā kūlana o kahi. No ka mālamaʻana i ka manawa lōʻihi, e mālama i ka lama i lalo -20 ° C.

    6-Bromo-4-chloroquinazoline.HCl (38267-96-8) pono e sila i kahi pahu pale, hoʻopaʻaʻia, a mai kahi hikiʻole o ke kanaka i kūʻoleʻia.

    Ma hope o ka hoʻohana

    Ma hope koke iho o ka lawelaweʻana i ka nūmāʻo 6-Bromo-4-chloroquinazoline.HCL, mālama i ke olakino kūpono ma ka holoiʻana i nā lima i ka nui o ka wai a me ke kopa.E hoʻopau i nā lole i haumia a holoiʻia i mua o ka hoʻohana houʻana iā lākou.

    E wehe i ka pahu ma ka hōʻiliʻiliʻana i nā huahana i hoʻohanaʻia, nāʻaila i hoʻopōʻinoʻia, nā'ōmole, nā leka, a me nā pahu hakahaka. E mālama mau i kēia mau moku i loko o kahi moku moku ma mua o ka hāʻawiʻana iā lākou i kahi hui pūnaewele laikini laikini.

    (38267-96-8) Nānā Hana Mua

    ʻO kahi ala pololei e hōʻole ai i nā pōʻino o ke olakino o 6-Bromo-4-chloroquinazoline.HCl paʻakai (38267-96-8) ma ke kauʻana i nā mea hana pilikino i'ōleloʻia. Pēlā,ʻo ka piliʻana me ka maka wai a me kahi ua palekana e hoʻemi ana i nā meaʻino'ē aʻe, i hiki ai i ka mea hoʻonāukiuki ke kumu. ʻO ka huahana i ka pilikino wale nō ke piliʻana i ke kino.

    Inhalation

    E hoʻoneʻe i kahi kanaka i kahi ākea. E nānā i nā'ōuli o ka pilikia, kaʻikeʻole, a me ka pōkole o ka hanu, a kākoʻo i ka hanuʻana me ka'ōhinu hana. I nā hana kūpono, e noi i ke kauka mai ke kauka.

    ʻO keʻano lapaʻau o kēia pilikia e hāpai nei i kahi hoʻolālā palekana a me ka hoʻohanaʻana i ka huahana i waho a iʻole kahi lumi me ka hoʻomaha loa o ka hau.

    ʻAina

    E hoʻomaʻemaʻe i ka waha no ka emiʻole o nā minuke 10. E inu i ka hapalua o ka meli o ka waiū a wai paha. E nānā i nā hōʻailona koʻikoʻi e like me ka nausea, ka diarrhea, a me ka'ākau, a eʻimi koke i ka lāʻau. A ināʻoe e hoʻopili i kahi kikowaena lāʻau lapaʻau a iʻole kauka paha, e lawe i kēia pepaʻike palekana meʻoe e kuhikuhi.

    ʻO kēia pilikia e pili pinepine ia i ka wā eʻai ai a inu ai paha me ka hoʻohanaʻana i ka 6-Bromo-4-chloroquinazoline.HCl paʻakai (38267-96-8). ʻO ka holoiʻoleʻana i nā lima ma hope o ka hoʻohanaʻia e hiki nō ke alakaʻi i kahi hāʻuleʻole.

    Ke Kino Kiko

    Inā ma nā maka, e hoʻokaʻawale i nā leka hulina a holoi me ke kau wela no nā minuke 15. E holoi ma ka hoʻokaʻawaleʻana i nā'ūpaka. Ma muli o ka likelike loa o ka 6-Bromo-4-chloroquinazoline.HCl paʻakai (38267-96-8) e'ānai ana i ka maka, e noi i ke kōkua kino.

    Ke hoʻokaʻaʻike aku ka huahana me kaʻili, e holoi i ka wahi me ka haunapona a me ka wai e holo ai a puni nā minuke 15.

    E hoʻomaopopo, i nā leka hulina a iʻole nā ​​lole i pokeʻia a me nā kāmaʻa e weheʻia ma mua o ka hoʻokōʻana i kēia kōkua mua.

    (38267-96-8) Ke Kaohi Kinai Ahi

    E like me ka mea e kau ai, pono e mālama i nāʻaukā palekana i ka wā e nānā aku ai i nā kinikino paʻakikī kūikawā .6-Bromo-4-chloroquinazoline.HCl (38267-96-8) hiki ke hoʻoheheʻeʻia i loko o ka kino make a me ka puhi i ke ahi. ʻO kēia waiwai ke koi nei i ka pono e komo i nā mea hoʻomaha hoʻomaha.

    E hoʻokuʻu i ke ahi me ke kalapona'okikene lua, ka pehu poli, aiʻole ka paukiko paʻapaʻa. Hiki ke hoʻopiliʻia kaʻili e hoʻopauʻia ma muli o keʻano wela a me ka mea nāna e hoʻopuka.

    Nā 6-Bromo-4-chloroquinazoline pahuhopu hōʻaho pilikia

    ʻOiaiʻaʻoleʻikeʻia nāʻikepili i ka 6-Bromo-4-chloroquinazoline.HCl paʻakai (38267-96-8) ma keʻano o ka abioaccumulativecompound me nā hopena o ka hopena o ka PBT, e mālama iāʻoeʻaʻole eʻae i ke komoʻana i nā papa wai.

    E hoʻomaʻemaʻe i nā'ōpala a me nā meaʻala e hui pū me kahi mea momona e like me ke one. Inā ma kahi kūpaʻa paʻa, e hoʻokala i nā lehulehu a hōʻiliʻili i loko o kahi pahu pani a hoʻonohonoho no ka hoʻolālā pono.

    Ke kūpaʻa a me ka hana hou o 6-Bromo-4-chloroquinazoline (38267-96-8)

    Mai hoʻokau i nā huahana ma lalo o nā mahana wela, ka mālamalama, nā ahi, ka mahana, a me nā kapuahi. Pēlā nō, hōʻole i ka hoʻoukuʻana i nā kumu waiwai, nā oxydants, aiʻole nā ​​waiū.ʻO kēia mau kumu ke kumu o ka hoʻokauʻia o ka 6-Bromo-4-chloroquinazoline.HCl paʻakai (38267-96-8), ka waiʻawaʻawa, CO2, HCl, NOx, a me HBr.

    ʻO ka 6-Bromo-4-chloroquinazoline kapae'ānai

    ʻO ka hoʻopauʻiaʻana o ka nūnē 6-Bromo-4-chloroquinazoline.HCl (38267-96-8) e kū i nā kulekele aupuni, ka moku'āina, a me nā pae honua. E hoʻokuʻi me nā luna i loaʻa i ka laikini no ka hoʻokuʻu maikaʻiʻana. E hoʻohui i ka hua me ka mea paleʻole a me ka wela i loko o ka umu ahi.

    6-Bromo-4-chloroquinazoline (38267-96-8) Shipping Shipping

    6-Bromo-4-chloroquinazoline.HCL paʻakai ka paʻakai no nāʻano kalepa i hoʻolakoʻia e hoʻoponoponoʻia nā mea.

    Nā Hoʻoponopono Hoʻomalu

    I kāu mālamaʻana i ka pa'ū 6-Bromo-4-chloroquinazoline.HCl (38267-96-8), e mālama i nā kānāwai kūpono.

    kōmike Details

    Aia nā'ōpili o APICMO i nā kānakaʻepekema hoʻolaʻa i kū ma waho o nā māhele a pau e pili ana i ka hoʻopiliʻana i ka lāʻau, ke noiʻi,ʻikeʻike lāʻau, meaʻike a me ke ola o ka honua, a me keʻano o nā kinikona.

    6-Bromo-4-chloroquinazoline (38267-96-8) Hoʻoponopono Kauwai a Hoʻolahalaha

    Hiki iāʻoe ke kauoha iā 6-Bromo-4-chloroquinazoline.HCL paʻakai i ka nui a iʻole nā ​​mea liʻiliʻi loa. E hōʻo inoaʻoe e lilo i mea hoʻohana inoa a loiloi e nānā i ka'ōlelo. E kāleka i kā mākouʻoihana lawelawe e hana i kahi kauoha.

    ʻia ....................

    1. Chem Sources International Directories Publishing Company Huiʻia, 2008, Kekaha Hana Hua, 1001-1010.
    2. Nā Pōʻalei i ka Hua'ōlelo Hua'ōlelo Hīkia, Volume 104, Hoʻoponoponoʻia e Alan R. Katritzky,ʻAoʻao 462.
    3. Ke KōmikeʻOihana No ka'Ipele'Eolahana, US. Ka Waihona Puke Lapaʻau o Hawaiʻi, Pubchem, 4,4-Difluorocyclohexanone, Paukū 1-9.

  2. Apicmo -

    ʻO kaʻenehana paʻakai 6-BroMo-4-chloroquinazoline.HCl kūikawā a me ka lawelawe āu i loaʻa ai,ʻike maikaʻi.

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