Tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6)

(2 Customer hōʻike manaʻo)

Ke noho nei kēia huahana ma kahi palapala pāʻani APICMO.

Ka hiki ke hoʻohua, synthesize a hana i nā mea nui o tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) me ka pūnaewele mana maikaʻi ma lalo o ka CGMPʻoihana
nā kauā.

Māhele:

Description

tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) video

ʻO Tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate. He pūlaʻiʻo Spiro i loko o nā mea hoʻopaneʻe kinase, e like me c - Kāhua i ka hana o nā mea pāʻani o tyrosine kinase a me like, a hiki ke hoʻohanaʻia no ka mālamaʻana i kēia kinase o nā maʻi i hanaʻia e nā hana maʻamau, e like me ke kanesa, aiʻole no ka hoʻomākaukauʻana i kahi nā lāʻau lapaʻau no ka mālamaʻana i kēia maʻi.

ʻO kāna mea hoʻohana he 1-oxa-6-aza-spiro- [2.5] octane-6-caboxylic acid tert-butyl ester, tert-Butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate, 6-aza -6-tert-butyloxycarbonyl-1-oxaspiro <2.5> octane, 1-oxa-6-aza-spiro [2,5] octane-6-carboxylic acid tert-butyl ester, 1-oxa-6-aza-spiro [2.5] octane-6-carboxylic acid tert-butyl ester, 1,1-dimethylethyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate, 1,1-dimethylethyl 1-oxa-6-azaspiro [2.5] octane -6-carboxylate.

Hoʻohanaʻiaʻo ia ma keʻano he mea lapaʻau waena. Hoʻohanaʻia nō hoʻi ia ma keʻano he mau kau waena o nā synthets organic.

Ke noho nei kēia huahana ma kahi palapala pāʻani APICMO. Ināʻikeʻoe i kēiaʻaoʻao ma keʻano he mea hoʻohanaʻoleʻia,ʻo ke kumukūʻai i hōʻikeʻia he List Price. No kaʻikeʻana i kāu kumukūʻai, e hoʻopaʻa i ka hoʻohanaʻana i kāu helu helu, aiʻole e liloʻoe i mea hoʻohana inoaʻia e ke kākoʻoʻana i kahi o kā mākou hui lawelawe. No ka hoʻonohonohoʻana i kahi kauoha, hoʻokaʻaʻike ʻO ka lawelawe lawelaweʻana a APICMO .

tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) Specifications

CAS 147804-30-6
Ke kaʻina CAS% 95.0
Kālena CAS Max% 98.0
MDL Number ʻO MFCD07779385
InChI Key ULSBMKGFFFMGOI-UHFFFAOYSA-N
Ka inoa inoa inoa o ka tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate
Pāʻani infrared pono
MālamaʻAlaʻAlua 97%
ʻO ke Kino Paleka Crystalline
'ōpala ʻO ka'ōmole Glass
Ka Lā Molecular C11H19NO3
Molecular Weight (g / mol) 213.277
SMILES CC (C) (C)'OC (= O) N1CCC2 (CC1) CO2
kala like 'ole Keʻokeʻo
Ka inoa inoa inoa Tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate
Point Hoʻolālā 56 ° i ka 58 ° C
ʻAna ≥96.0%

Tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) Ke kūlana palekana a me ka lawelaweʻana

(147804-30-6) Hōʻikeʻikepili:

Hana i ka huhūʻili.

Hana i nā maka o ka maka.

Hiki ke hoʻonāukiuki i ka hanu hau.

Makeʻa i ka hanuʻana i ka lepo / fume / gas / mist / vapors / spray.

Tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate Ka'ōlelo kūkākūkā:

Makeʻa i ka hanuʻana i ka lepo / fume / gas / mist / vapors / spray.

Wewe pale lima pale / pale pale / pale maka / pale pale.

KA HANA I KA EYES: Hoʻoholo me ka nānā me ka wai no nā minuke. Wehe i nā leka hulina, inā he mau a hiki ke maʻalahi. E hoʻomau i ka holoi.

KA HOPE: E hoʻokuʻu i ka ea ea e hoʻomalu i ka hanu. E kūʻai i ka mea i hoʻopaʻaʻia.

Hoʻokaʻawale i nā mea / ipu me nā kūlana o ka moku / ka 'āina / aupuni / ka honua.

'Ōlelo Aʻo: Ua hoʻokumuʻia kaʻike i hoʻolakoʻia ma kēia pūnaewele e like me nā kānāwai o ka Europa (EU) a ua kūpono i ka maikaʻi o ko mākouʻike, kaʻike a me ka manaʻo i ka lā o kona hoʻolahaʻana. ʻO kaʻike i hāʻawiʻia i kūkuluʻia wale nōʻo ia ke alakaʻi no ka mālama pono a hoʻohanaʻana. ʻAʻole pono e noʻonoʻoʻia e like me ke kikowaena a iʻole ke kiko kiko'ī.

tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) Articles

Nafizal Hossain

Nafizal Hossain, et al. Nā pūhui spirocyclic, CCR1 antagonists.Bioorg pono. ʻO Med. ʻO Chem. Lett., 2013

Nānā Hanahana:

Loaʻa kaʻike o kā mākou pūʻuluʻepekema ma nā wahi noiʻi a pau e pili ana i Life Science, Material Science, Synthesis Chemical, Chromatography, Analytical a me nā mea'ē aʻe.

Tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) Kūpena Paipai & Pricing:

Loaʻa i nā mea nui no kāu kūkuluʻana, hana hana a noiʻi noiʻi paha?


=

2 hōʻike manaʻo no ka mea, Tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6)

  1. APICMO -

    ʻO ka Hoʻohālikelike Kōnae-Hoʻohālike i ka tert-butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6)

    Hana mākou a synthesi i ka Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate ma ka nui a ma ka nui. Ma APICMO, hoʻopili nā hualoaʻa a pau i nā kaʻina hana o ka mana cGMP. Inā makemakeʻoe e kūʻai i nā nui a iʻole nāʻano liʻiliʻi o kēia huahana, a laila aiaʻoe ma kahi'ākau. E kau wale i kahi kauoha ma ke kālekaʻana i kā mākou mau alakaʻi hoʻoponopono hoʻokipa a me nā meaʻoihana lawelawe. Inā makemakeʻoe eʻike i kaʻike hou e pili ana i ka huahana, e hoʻomau i ka heluheluʻana.

    Nert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate Hōʻike

    ʻO ka'ōpiko -butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate i hāʻule i loko o ka māhele o ka pūhui spiro. Hōʻike nā haʻawina e hiki ke hana i mea hōʻailona o kinases, e like me tyrosine. Ma hope o kēia, ua alakaʻiʻia i kaʻike lāʻau i ka mālamaʻana a me ka mālamaʻana i nā meaʻinoʻole e pili ana i kinase, e hoʻomaka ana i ka holoʻana o ka maʻi.

    ʻOiai he lāʻau lapaʻau waena ia,ʻo ka huahana kekahi meaʻoi aku i loko o keʻano o keʻano o ka hoʻohui mele.

    ʻO ke kumu hoʻohālikelike o ka Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6):

    tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6)

    Nert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate Kūkākūkā

    ʻAʻole CAS no. 147804-30-6
    Inoa inoa inoa 1-oxa-6-azaspiro [2.5] octane-6-carboxylic acid tert-butyl ester
    'Aiha (g / cm3) 1.123
    Keʻano hoʻolālā C11H19ʻAʻOLE3
    Ka pae paila (˚C) 297.62
    Pākuhi Flash (˚C) 133.8
    Inoa IUPAC Nert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate
    Ka pae hoʻolālā (˚C) 55 - 59
    ʻO ke kaumaha kaulike (g / mol) 213.277
    Ka monoisotopic mass (g / mol) 213.136
    ʻO ke kino paa
    Purity 97%
    ʻO ke kumuhana hana
    'O Synonyms · 6- (tert-Butoxycarbonyl) -1-oxa-6-azaspiro [2.5] octane
    · 6-boc-1-oxa-6-azaspiro [2.5] octane
    · 1-oxa-6-azaspiro [2.5] octane-6-carboxylic acid tert-butyl ester
    · 1-oxa-6-azaspiro [2.5] octane-6-carboxylate
    · 1-oxa-6-azaspiro [2.5] octane-6-carboxylic acid tert-butyl ester
    · Tert-butyl-6-azaspiro [2.5] octane-1-oxa-6-carboxylate.

    NĀ Kino a me nā Pono Kino o Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6)

    Keʻano

    ʻO Nert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate kahi meaʻaila kilokilo keʻokeʻo.

    147804-30-6 pūnaewele

    Ka loulou paʻa 2
    Kahi paʻa wai Helu helu Donor - 1 pūnaewele

    Helu helu kiʻi - 3

    Kohu 1

    Nā 147804-30-6 Mea Hana i hoʻoiliʻia

    Kahi inoa ʻO ke kumu waiwai
    XLogP3-AA 1.1
    Kaohi kaohi (mmHg) 0.0 ± 6
    Ka helu helu hōʻemiʻole 0
    ʻO ka heluʻo Atom Stereocenter 0
    Wahi puni pola 42.07 A '2
    Hōʻike kuhikuhi 1.506
    Hoʻomākaukauʻo Isotope Atom 0
    Heluhelu Atomona Heavy 15
    Kāleka Kūikawā 0
    ʻIke kūpono (g / mol) 213.136
    Ka Heluhelu Hoʻohālike Bond Bond 0
    Hoʻomākaukau'Āina Atom 0
    Hoʻokomoʻia ka papahana ʻAe
    Ka nui 262

    Kahi Kūʻai Kūlanaʻo Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate

    ʻEiwa mau ala kuhikuhi no kēia huahana. Ma lalo iho nei kekahi mauʻano i manaʻoʻia:

    Tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6)

    Tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6)

    Nā noi o 147804-30-6ʻO nā&#39;āpana&#39;ōpala APICMO

    • ʻOhana ma keʻano he mea lapaʻau a me ke kōkiko koʻikoʻi
    • He mea pale i kekahi kinamela kinases

    147804-30-6 Hazard Description

    • Maʻemaʻe paha i ka hoʻonāukiukiʻana i nā maka, e hiki ai i ka pōʻino mau loa
    • Hiki ke hana i nā meaʻeleʻeleʻili
    • ʻO ka mumū o ka'ōpū hanu

    Nā Paʻa Haumāna I ka Hanaʻana me Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6)

    1. Ke Kuleana pilikino

    Nā mea pale

    Pono nā mea pono e like me nā kuhikuhi o ka moku, e like me nā kānāwai o Europa (EU) no ka'āinaʻEulopa a NIOSH noʻAmelika Hui PūʻIa. E hōʻoiaʻiʻo i ka palekana o ke kino, nā maka, ke alo, nā'ōpū a me kaʻili. E hoʻohana i kaʻano N95 a iʻole e hoʻokau i nā masks P1 ma muli o nā hoʻoponopono o ka'āina.

    Nert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) Mana mana hoʻokele

    E hōʻoia i ka hoʻolālā a me ka ua palekana o kāu wahi hana.

    2. ʻO nā mea kōkua mua

    Nānā maka

    E hoʻomaʻemaʻe i nā maka me ka wai me ka wai anuanu no nā mau minuke 15 e hiki mai nei. Loaʻa i ke kōkua inā loaʻa ka huhū.

    Hoʻokaʻaʻike Pelekane

    E holoi me nā wai a me nā kopa no nā minuke 15.

    ʻAina

    ʻO ke kōkua mua ke pili wale nō i ka wā eʻike ai ka mea hewa. Hoʻopili i ka waha a inu a inu i ka hapalua o ka lita o ka wai aiʻole ka waiū. Keʻikeʻoleʻia ka meaʻeha, e kōkua koke mai i kahi kikowaena lāʻau, kahi meaʻoni loʻi, aiʻole kauka.

    Inhalation

    E hoʻoneʻe i ka mōhai i kahi lumi i hoʻolālāʻia e mālama i kahi noho hoʻomaha. Hoʻonohonoho i ka respiration artificial i ka manawa eʻikeʻoleʻia ai ka mea pepehi kanaka a loaʻa koke mai ka kōkua mai ke kauka.

    3. Nānāʻana i ka Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate

    Ke hoʻohanaʻia, e nānā i kēia mau'ōlelo ma hope nei:

    • E hōʻoki i ka hanuʻana, ka noe, ka mahu, a iʻole nā ​​meaʻino'ē aʻe
    • Lawe mākou i nā lako palekana pilikino i'āponoʻia
    • E hoʻohana iā ia i loko o ka hale hoʻolālā i hāmama

    4. Kaomi o Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6)

    Ke hoʻohanaʻoleʻia,

    • E kūʻai i loko o nā kūlana maʻamau
    • E mālama i ka huahana ma lalo o ka meaola
    • E hoʻopaʻa i ka hakahaka o ka pahu waihona
    • E hōʻoia i kahi i mālamaʻia, kahi maloʻo, a maloʻo
    • E mālama i ka Nert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate mai kahi o nā mea hoʻonāukiuki.
    • Hoʻokuʻu i ka Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate e kaupalena ai i ka

    5. Ma hope o ka hoʻohana

    Ma hope o ka hoʻohanaʻana i ka Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate,

    • E wehe i nā meahana i hoʻohanaʻia a iʻole nā ​​mea i hoʻopōʻinoʻia
    • E holoi lima
    • E hoʻihoʻi i ka huahana i hoʻohanaʻoleʻia i ka moku momona mua
    • E wehe i ka papa hana ma ka holoiʻana i nā wīwī

    6. Ke ahi

    Hoʻokomo i ka hāʻana o ka hanuʻana no ka paleʻana i kahi kūpilikiʻi me nā'ōpala a me nā nalu maʻamau, e ala mai ana mai ka hopena. E hoʻopau i ka lapalapa ahi me ka mīkini wai, ka maloʻo maloʻo maloʻo, ka mea hoʻonā'āina i ka waiʻona, aiʻole carbon dioxide. Hiki ke hoʻopauʻia ka pāhana e hoʻopauʻia ma muli o ka nui o ke ahi a me ka mea nāna e hoʻopuka.

    7. Nā Hoʻokuʻu Haʻawina Noi

    Loaʻa i nā leka a me nā pū'ā. Hoʻopiʻi i ka pupuhi a hoʻohana paha i kahi inert absorbent e like me ke one e hoʻonui i ka mea hana. E hoʻolei i loko o kahi pahu pani a waihoʻia e like me nā hoʻoponopono hoʻolālā o ka'āina.

    8. Ke kūpaʻa a me ke kūpaʻa o ka Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate

    Kūpaʻa ka huahana ma lalo o nā kūlana hoʻonaʻauao maʻamau.

    9. 147804-30-6 Kelepona'Ile

    Hoʻohui i ka Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate e like me ke kūlana kūikawā a hoʻoleiʻia me ke kōkua o kahi hui pūnaewele laikini.

    10. Ka Palapala Paʻa

    ʻO Nert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) ka meaʻawaʻawaʻole no ka ea, kaʻili, aiʻole ka lawe moanaʻana.

    Nert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6)ʻIkepili Hoʻolaha

    ʻO Nert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6)ʻaʻohe kūkaʻina kūikawā a iʻole mau pōʻino i ka hoʻokele, ke ola kanaka, aʻole ka honua. no ke kumu o ka hoʻomauʻana a no ka bioaccumulative. No kēia kumu, ua hoʻohālikeʻia heʻano weliweli aʻaʻohe kūlana weliweli paha.

    ʻO kaʻikepili i loko nei e kūlike nei ia me nā koi o ka honua.

    kōmike Details

    Heʻike kūpono ko mākou mauʻepekema i nā haʻawina waiwai a me ke ola o ka honua, nā kānā kilokilo, ka chromatography, ke kiʻikuʻu mele, a me ka noiʻiʻepekema.

    Nert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate Bulk Hoʻonohonoho a me ke ukuʻana.

    Loaʻa i ka noiʻi, hoʻolālā, a me nā hōʻawe o nā kinetona? E mālama i nā mea nui o ka Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate mai iā mākou a loaʻa ka'ūpī. E kāleka iā mākou e kau i kahi kauoha.

    ʻia ....................

    1. Ke KōmikeʻOihana No ka'Ipele'Eolahana, US. Ka Hale Waihona Puke Lapaʻau, Pubchem, Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate, Mahele 1-10.
    2. ʻO Nafizal Hossaina Svetl IvanoʻO Jonas BergareaʻO Tomas Eriksson, nā pūhui Spirocyclical, nā meaʻokoʻa CCR1 paha, nā meaola lāʻau a me nā lāʻau lapaʻau Kēkelē Volume 23, Hua'ōlelo 6, 15 Malaki 2013, NāʻAoʻao 1883-1886.
    3. Ali Nasrallah Gwendal Grelier Maria Ivana Lapuh Fernando J. Duran Benjamin Darses Philippe Dauban, Dirdem (II) - Hoʻopiʻiʻiaʻo Alkene Epoxidation me Iodine (III)'Oxidants,ʻaoʻao 12-14.
  2. Apicmo -

    ʻO ka mea maikaʻi loaʻo Tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate a me ka lawelawe i loaʻa iaʻu,ʻo kaʻike maikaʻi.

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